SocPhilSciPract · @SocPhilSciPract
14th Sep 2019 from TwitLonger
Panel July 2020 SPSP Mechanistic/Medicine
Dear SPSP meeting participants,
For the July 2020 SPSP meeting I’d like to organize a session with papers that apply the new mechanistic philosophy of science to topics in the philosophy of medicine. My own work applies it to the ontology and representation of genetic disease mechanisms to aid mechanism discovery. But there are potentially many other possible topics: the on-going debate about the role of mechanisms in evidence based medicine; mechanisms and drug discovery; the relation of knowing the mechanism of action of a drug and a patient’s ethical views; and ??? If you are interested, please contact me: darden@umd.edu
Lindley Darden
Research Professor
University of Maryland, College Park
USA
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Suggested references on mechanisms and medicine
Clarke, Brendan, Donald Gillies, Phyllis Illari, Federica Russo & Jon Williamson (2014), "Mechanisms and the Evidence Hierarchy," Topoi 33(2): 339-360.
Topoi doi: 10.1007/s11245-013-9220-9, 2013.
Craver, Carl F. and Lindley Darden (2013), In Search of Mechanisms: Discoveries across the Life Sciences. Chicago, IL: University of Chicago Press.
Darden, Lindley, Lipika R. Pal, Kunal Kundu, and John Moult (2018), "The Product Guides the Process: Discovering Disease Mechanisms," in Building Theories: Heuristics and Hypotheses in the Sciences. Edited by David Danks and Emiliano Ippoliti. Cham, Switzerland: Springer International Publishing, pp. 101-117.
Preprint: http://philsci-archive.pitt.edu/13176/
Darden, Lindley, Kunal Kundu, Lipika R. Pal, and John Moult (2018), "Harnessing Formal Concepts of Biological Mechanism to Analyze Human Disease," PLoS Computational Biology 14 (12): e1006540. [%22]https://doi.org/10.1371/journal.pcbi.1006540
Glennan, Stuart and Phyllis Illari (eds.) (2017), The Routledge Handbook of Mechanisms and Mechanical Philosophy. New York: Routledge.
Illari, Phyllis McKay (2011), "Mechanistic Evidence: Disambiguating the Russo-Williamson Thesis," International Studies in Philosophy of Science 25 (2): 139-157.
DOI:10.1080/02698595.2011.574856
Kennedy, Ashley and Sarah Malanowski, (2019), "Mechanistic Reasoning and Informed Consent," Bioethics 33(1): 162-168. https://doi.org/10.1111/bioe.12500
Machamer, Peter, Lindley Darden, and Carl F. Craver (2000), "Thinking About Mechanisms," Philosophy of Science 67: 1-25.
Parkkinen, V.-P., Wallmann, C., Wilde, M., Clarke, B., Illari, P., Kelly, M.P., Norell, C., Russo, F., Shaw, B., Williamson, J. (2018), Evaluating Evidence of Mechanisms in Medicine: Principles and Procedures. Springer Briefs in Philosophy. Open access: https://link.springer.com/book/10.1007%2F978-3-319-94610-8
Russo, Federica and Jon Williamson (2007), "Interpreting Causality in the Health Sciences," International Studies in the Philosophy of Science 21 (2): 157-170.